Amyloid-Beta-Related Angiitis with Distinctive Neuro-Ophthalmologic Features.

ABSTRACT: Amyloid beta-related angiitis (ABRA) is a subtype of cerebral amyloid angiopathy-related inflammation, with distinctive pathology and prognosis compared with cerebral amyloid angiopathy (CAA). On a spectrum of increasing severity, ABRA is considered to be in-between the less aggressive inflammatory-CAA and the more severe primary central nervous system (CNS) angiitis. Whereas retinal pathological changes were described in subjects with primary or secondary CNS angiitis, and non-inflammatory CAA, bilateral posterior pole superficial and peripapillary retinal hemorrhages have not been reported as initial signs in patients with pathology-confirmed ABRA, accompanying neurological spells and characteristic neuroimaging findings.

SUBMITTER: Dumitrascu OM 

PROVIDER: S-EPMC6056207 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature