Ontology highlight
ABSTRACT:
SUBMITTER: Hijano DR
PROVIDER: S-EPMC6056463 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Hijano Diego R DR Siefker David T DT Shrestha Bishwas B Jaligama Sridhar S Vu Luan D LD Tillman Heather H Finkelstein David D Saravia Jordy J You Dahui D Cormier Stephania A SA
Scientific reports 20180723 1
Respiratory syncytial virus (RSV) infection is the most frequent cause of hospitalization in infants and young children worldwide. Although mucosal RSV vaccines can reduce RSV disease burden, little is known about mucosal immune response capabilities in children. Neonatal or adult mice were infected with RSV; a subset of neonatal mice received interferon alpha (IFN-α) (intranasal) prior to RSV infection. B cells, B cell activating factor (BAFF) and IgA were measured by flow cytometry. RSV specif ...[more]