Ontology highlight
ABSTRACT:
SUBMITTER: Wu J
PROVIDER: S-EPMC6056621 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Frontiers in pharmacology 20180717
Nanoparticles (NPs) have demonstrated a potential for hepatocarcinoma therapy. However, the effective and safe NP-mediated drug transportation is still challenging due to premature leakage and inaccurate release of the drug. Herein, we designed a series of core cross-linking galactose-based glycopolymer-drug conjugates (GPDs) NPs with both redox-responsive and pH-sensitive characteristics to target and program drug release. Glycopolymer is comprised of galactose-containing units, which gather on ...[more]