Levosimendan in pulmonary hypertension and right heart failure.
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ABSTRACT:
SUBMITTER: Hansen MS
PROVIDER: S-EPMC6058424 | biostudies-literature | 2018 Jul-Sep
REPOSITORIES: biostudies-literature
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Levosimendan in pulmonary hypertension and right heart failure.
Hansen Mona Sahlholdt MS Andersen Asger A Nielsen-Kudsk Jens Erik JE
Pulmonary circulation 20180706 3
Pulmonary hypertension is a multifactorial disease with a high morbidity and mortality. Right ventricular function is the most important predictor of morbidity and mortality in patients suffering from pulmonary hypertension, but currently there are no approved treatments directly supporting the failing right ventricle. Levosimendan is a calcium sensitizing agent with inotropic, pulmonary vasodilatory, and cardioprotective properties. Given its pharmacodynamic profile, levosimendan could be a pot ...[more]
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