Ontology highlight
ABSTRACT: Introduction
Antiretroviral therapy reduces the risk of serious illness among people living with HIV and can prevent HIV transmission. We implemented a Test, Treat, and Prevent HIV Program among men who have sex with men (MSM) and transgender women at five hospitals in four provinces of Thailand to increase HIV testing, help those who test positive start antiretroviral therapy, and increase access to pre-exposure prophylaxis (PrEP).Methods
We implemented rapid HIV testing and trained staff on immediate antiretroviral initiation at the five hospitals and offered PrEP at two hospitals. We recruited MSM and transgender women who walked-in to clinics and used a peer-driven intervention to expand recruitment. We used logistic regression to determine factors associated with prevalent HIV infection and the decision to start antiretroviral therapy and PrEP.Results
During 2015 and 2016, 1880 people enrolled. Participants recruited by peers were younger (p<0.0001), less likely to be HIV-infected (p<0.0001), and those infected had higher CD4 counts (p = 0.04) than participants who walked-in to the clinics. Overall, 16% were HIV-positive: 18% of MSM and 9% of transgender women; 86% started antiretroviral therapy and 46% of eligible participants started PrEP. A higher proportion of participants at hospitals with one-stop HIV services started antiretroviral therapy than other hospitals. Participants who started PrEP were more likely to report sex with an HIV-infected partner (p = 0.002), receptive anal intercourse (p = 0.02), and receiving PrEP information from a hospital (p<0.0001).Conclusions
We implemented a Test, Treat, and Prevent HIV Program offering rapid HIV testing and immediate access to antiretroviral therapy and PrEP. Peer-driven recruitment reached people at high risk of HIV and people early in HIV illness, providing an opportunity to promote HIV prevention services including PrEP and early antiretroviral therapy. Sites with one-stop HIV services had a higher uptake of antiretroviral therapy and PrEP.
SUBMITTER: Ongwandee S
PROVIDER: S-EPMC6059477 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Ongwandee Sumet S Lertpiriyasuwat Cheewanan C Khawcharoenporn Thana T Chetchotisak Ploenchan P Thiansukhon Ekkachai E Leerattanapetch Niramon N Leungwaranan Banlang B Manopaiboon Chomnad C Phoorisri Thanongsri T Visavakum Prin P Jetsawang Bongkoch B Poolsawat Monsicha M Nookhai Somboon S Vasanti-Uppapokakorn Monthinee M Karuchit Samart S Kittinunvorakoon Chonticha C Mock Philip P Prybylski Dimitri D Sukkul Ake-Chittra AC Roels Thierry T Martin Michael M
PloS one 20180725 7
<h4>Introduction</h4>Antiretroviral therapy reduces the risk of serious illness among people living with HIV and can prevent HIV transmission. We implemented a Test, Treat, and Prevent HIV Program among men who have sex with men (MSM) and transgender women at five hospitals in four provinces of Thailand to increase HIV testing, help those who test positive start antiretroviral therapy, and increase access to pre-exposure prophylaxis (PrEP).<h4>Methods</h4>We implemented rapid HIV testing and tra ...[more]