White Matter Deficits Underlying the Impaired Consciousness Level in Patients with Disorders of Consciousness.
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ABSTRACT:
SUBMITTER: Wu X
PROVIDER: S-EPMC6060210 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
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White Matter Deficits Underlying the Impaired Consciousness Level in Patients with Disorders of Consciousness.
Wu Xuehai X Zhang Jiaying J Cui Zaixu Z Tang Weijun W Shao Chunhong C Hu Jin J Zhu Jianhong J Zhao Yao Y Lu Lu L Chen Gang G Northoff Georg G Gong Gaolang G Mao Ying Y He Yong Y
Neuroscience bulletin 20180709 4
In this study, we aimed to (1) identify white matter (WM) deficits underlying the consciousness level in patients with disorders of consciousness (DOCs) using diffusion tensor imaging (DTI), and (2) evaluate the relationship between DTI metrics and clinical measures of the consciousness level in DOC patients. With a cohort of 8 comatose, 8 unresponsive wakefulness syndrome/vegetative state, and 14 minimally conscious state patients and 25 patient controls, we performed group comparisons of the D ...[more]
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