Ontology highlight
ABSTRACT:
SUBMITTER: Othman AS
PROVIDER: S-EPMC6060232 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Othman Ahmad Syibli AS Franke-Fayard Blandine M BM Imai Takashi T van der Gracht Esmé T I ETI Redeker Anke A Salman Ahmed M AM Marin-Mogollon Catherin C Ramesar Jai J Chevalley-Maurel Séverine S Janse Chris J CJ Arens Ramon R Khan Shahid M SM
Frontiers in cellular and infection microbiology 20180719
Protection against a malaria infection can be achieved by immunization with live-attenuated <i>Plasmodium</i> sporozoites and while the precise mechanisms of protection remain unknown, T cell responses are thought to be critical in the elimination of infected liver cells. In cancer immunotherapies, agonistic antibodies that target T cell surface proteins, such as CD27, OX40 (CD134), and 4-1BB (CD137), have been used to enhance T cell function by increasing co-stimulation. In this study, we have ...[more]