Ontology highlight
ABSTRACT:
SUBMITTER: Ulusoy M
PROVIDER: S-EPMC6060716 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Ulusoy Mehriban M Lavrentieva Antonina A Walter Johanna-Gabriela JG Sambale Franziska F Green Mark M Stahl Frank F Scheper Thomas T
Toxicology research 20150807 1
In this work, three-dimensional (3D) spheroid cultures of human adipose-derived mesenchymal stem cells (hAD-MSCs), with tissue-mimetic morphology through well developed cell-cell and cell-matrix interactions and distinct diffusion/transport characteristics, were assessed for dose-dependent toxic effects of red-emitting CdTe/CdS/ZnS quantum dots (Qdots). Morphological investigations and time-resolved microscopy analysis in addition to cell metabolic activity studies revealed that 3D spheroid cult ...[more]