The hypothalamic-pituitary-testicular axis and the testicular function are modulated after silver nanoparticle exposure.
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ABSTRACT:
SUBMITTER: Cavallin MD
PROVIDER: S-EPMC6060733 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
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The hypothalamic-pituitary-testicular axis and the testicular function are modulated after silver nanoparticle exposure.
Cavallin M D MD Wilk R R Oliveira I M IM Cardoso N C S NCS Khalil N M NM Oliveira C A CA Romano M A MA Romano R M RM
Toxicology research 20171123 1
Silver nanoparticles (AgNPs) are widely used in industrial and medical applications and humans may be exposed through different routes, increasing the risk of toxicity. We investigated the transcript expression of genes involved in the regulation of the hypothalamic-pituitary-testicular (HPT) axis and the parameters associated with sperm functionality after prepubertal exposure. AgNPs modulated the transcript expression of genes involved in the control of the HPT axis and spermatogenesis in the ...[more]
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