Ontology highlight
ABSTRACT:
SUBMITTER: Kumar P
PROVIDER: S-EPMC6063478 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Kumar Pardeep P Kuhlmann F Matthew FM Chakraborty Subhra S Bourgeois A Louis AL Foulke-Abel Jennifer J Tumala Brunda B Vickers Tim J TJ Sack David A DA DeNearing Barbara B Harro Clayton D CD Wright W Shea WS Gildersleeve Jeffrey C JC Ciorba Matthew A MA Santhanam Srikanth S Porter Chad K CK Gutierrez Ramiro L RL Prouty Michael G MG Riddle Mark S MS Polino Alexander A Sheikh Alaullah A Donowitz Mark M Fleckenstein James M JM
The Journal of clinical investigation 20180625 8
Enterotoxigenic Escherichia coli (ETEC) infections are highly prevalent in developing countries, where clinical presentations range from asymptomatic colonization to severe cholera-like illness. The molecular basis for these varied presentations, which may involve strain-specific virulence features as well as host factors, has not been elucidated. We demonstrate that, when challenged with ETEC strain H10407, originally isolated from a case of cholera-like illness, blood group A human volunteers ...[more]