Ontology highlight
ABSTRACT:
SUBMITTER: Domenech de Celles M
PROVIDER: S-EPMC6063734 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Domenech de Cellès Matthieu M Magpantay Felicia M G FMG King Aaron A AA Rohani Pejman P
Science translational medicine 20180301 434
The resurgence of pertussis over the past decades has resulted in incidence levels not witnessed in the United States since the 1950s. The underlying causes have been the subject of much speculation, with particular attention paid to the shortcomings of the latest generation of vaccines. We formulated transmission models comprising competing hypotheses regarding vaccine failure and challenged them to explain 16 years of highly resolved incidence data from Massachusetts, United States. Our result ...[more]