Ontology highlight
ABSTRACT:
SUBMITTER: Song W
PROVIDER: S-EPMC6063939 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Song Wenyu W Huang Hailiang H Zhang Cheng-Zhong CZ Bates David W DW Wright Adam A
Scientific reports 20180727 1
Genome-wide association studies depend on accurate ascertainment of patient phenotype. However, phenotyping is difficult, and it is often treated as an afterthought in these studies because of the expense involved. Electronic health records (EHRs) may provide higher fidelity phenotypes for genomic research than other sources such as administrative data. We used whole genome association models to evaluate different EHR and administrative data-based phenotyping methods in a cohort of 16,858 Caucas ...[more]