Ontology highlight
ABSTRACT:
SUBMITTER: Bakir M
PROVIDER: S-EPMC6064662 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Bakir Maral M Jackson Nicholas J NJ Han Simon X SX Bui Alex A Chang Eleanor E Liem David A DA Ardehali Abbas A Ardehali Reza R Baas Arnold S AS Press Marcella Calfon MC Cruz Daniel D Deng Mario C MC DePasquale Eugene C EC Fonarow Gregg C GC Khuu Tam T Kwon Murray H MH Kubak Bernard M BM Nsair Ali A Phung Jennifer L JL Reed Elaine F EF Schaenman Joanna M JM Shemin Richard J RJ Zhang Qiuheng J QJ Tseng Chi-Hong CH Cadeiras Martin M
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20180322 8
<h4>Background</h4>Survival after heart transplantation (HTx) is limited by complications related to alloreactivity, immune suppression, and adverse effects of pharmacologic therapies. We hypothesize that time-dependent phenomapping of clinical and molecular data sets is a valuable approach to clinical assessments and guiding medical management to improve outcomes.<h4>Methods</h4>We analyzed clinical, therapeutic, biomarker, and outcome data from 94 adult HTx patients and 1,557 clinical encounte ...[more]