Ontology highlight
ABSTRACT:
SUBMITTER: Krawczyk K
PROVIDER: S-EPMC6064724 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Krawczyk Konrad K Kelm Sebastian S Kovaltsuk Aleksandr A Galson Jacob D JD Kelly Dominic D Trück Johannes J Regep Cristian C Leem Jinwoo J Wong Wing K WK Nowak Jaroslaw J Snowden James J Wright Michael M Starkie Laura L Scott-Tucker Anthony A Shi Jiye J Deane Charlotte M CM
Frontiers in immunology 20180723
Every human possesses millions of distinct antibodies. It is now possible to analyze this diversity <i>via</i> next-generation sequencing of immunoglobulin genes (Ig-seq). This technique produces large volume sequence snapshots of B-cell receptors that are indicative of the antibody repertoire. In this paper, we enrich these large-scale sequence datasets with structural information. Enriching a sequence with its structural data allows better approximation of many vital features, such as its bind ...[more]