Ontology highlight
ABSTRACT:
SUBMITTER: Filareto A
PROVIDER: S-EPMC6064991 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Filareto Antonio A Maguire-Nguyen Katie K Gan Qiang Q Aldanondo Garazi G Machado Léo L Chamberlain Jeffrey S JS Rando Thomas A TA
Proceedings of the National Academy of Sciences of the United States of America 20180709 30
Duchenne muscular dystrophy (DMD) is a rare, muscle degenerative disease resulting from the absence of the dystrophin protein. DMD is characterized by progressive loss of muscle fibers, muscle weakness, and eventually loss of ambulation and premature death. Currently, there is no cure for DMD and improved methods of disease monitoring are crucial for the development of novel treatments. In this study, we describe a new method of assessing disease progression noninvasively in the <i>mdx</i> model ...[more]