Ontology highlight
ABSTRACT:
SUBMITTER: Ochiai A
PROVIDER: S-EPMC6065317 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Ochiai Akihito A Ogawa Kodai K Fukuda Minami M Ohori Masahiro M Kanaoka Takumi T Tanaka Takaaki T Taniguchi Masayuki M Sagehashi Yoshiyuki Y
Scientific reports 20180730 1
Fungal infections, such as candidiasis and aspergillosis, are some of the most frequent infections in humans. Although antifungal drugs are available for the treatment of these infections, antifungal agents with new mechanisms of action should be developed because of the increasing incidence of drug-resistant pathogens in recent years. In this study, a basic functional analysis of rice defensin OsAFP1, a novel antifungal drug candidate, was conducted. OsAFP1 exerted fungicidal activity against C ...[more]