Ontology highlight
ABSTRACT:
SUBMITTER: Li G
PROVIDER: S-EPMC6067017 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Li Guannan G Wang Xin X Wang Xiuwei X Guan Zhen Z Guo Jin J Wang Fang F Zhang Jianzhao J Niu Bo B Zhang Ting T Wang Jianhua J Yang Jian J
Medical science monitor : international medical journal of experimental and clinical research 20180719
BACKGROUND DNA Base Excision Repair Gene-DNA LigaseIII (LIG3) is an important repair gene in the repair pathway and plays an important role in maintaining the integrity of mitochondria. Rs1052536 and rs3135967 polymorphisms of the gene are associated with lung cancer, keratoconus, and Fuchs endothelial corneal dystrophy. There is no previously published report on the relationship between the polymorphisms and neural tube defects (NTDs). MATERIAL AND METHODS Mass ARRAY iPLEX was used to determine ...[more]