Ontology highlight
ABSTRACT:
SUBMITTER: Storti S
PROVIDER: S-EPMC6068040 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Storti Sergio S Spina Michele M Pesce Emanuela Anna EA Salvi Flavia F Merli Michele M Ruffini Alessia A Cabras Giuseppina G Chiappella Annalisa A Angelucci Emanuele E Fabbri Alberto A Liberati Anna Marina AM Tani Monica M Musuraca Gerardo G Molinari Annalia A Petrilli Maria Pia MP Palladino Carmela C Ciancia Rosanna R Ferrario Andrea A Gasbarrino Cristiana C Monaco Federico F Fraticelli Vincenzo V De Vellis Annalisa A Merli Francesco F Luminari Stefano S
Haematologica 20180510 8
We conducted a phase II study to assess activity and safety profile of bendamustine and rituximab in elderly patients with untreated diffuse large B-cell lymphoma (DLBCL) who were prospectively defined as frail using a simplified version of the Comprehensive Geriatric Assessment (CGA). Patients had to be over 70 years of age, with histologically confirmed DLBCL. Frail patients were those younger than 80 years with a frail profile at CGA or older than 80 years with an unfit profile. Treatment con ...[more]