Ontology highlight
ABSTRACT:
SUBMITTER: Pinkas A
PROVIDER: S-EPMC6069300 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Pinkas Adi A Cunha Martins Airton A Aschner Michael M
International journal of environmental research and public health 20180704 7
The receptor for advanced glycation end products (RAGE), a multi-ligand receptor, is mostly associated with promoting inflammation and oxidative stress. In addition to advanced glycation end products (AGEs), its ligands include High mobility group box 1 protein (HMGB-1), S-100 proteins and beta-sheet fibrils. The effects of several metals and metalloids on RAGE expression and activation have been recently studied: in vivo and in vitro exposure to methylmercury, selenium, zinc, manganese, and ars ...[more]