Dataset Information

Racial/Ethnic Disparities in the Lifetime Risk of Chlamydia trachomatis Diagnosis and Adverse Reproductive Health Outcomes Among Women in King County, Washington.

ABSTRACT: Background:Chlamydia trachomatis is the most common reportable infection in the United States and can cause pelvic inflammatory disease (PID) and tubal factor infertility (TFI). Methods:We created life tables to estimate the "lifetime" risk of chlamydia diagnosis among women aged 15-34 years in King County, Washington, between 1992 and 2014. We estimated the lifetime risk of chlamydia-associated PID and TFI incorporating published estimates of the risk of sequelae. Results:There were 51464 first chlamydia diagnoses in 1992-2014. For women born between 1980 and 1984, the lifetime risk of chlamydia diagnosis was 19.8% overall and 14.0% for non-Hispanic white, 64.9% for non-Hispanic black, and 32.6% for Hispanic women. The cumulative risk of chlamydia by age 24 increased overall from 13.9% to 17.3% among women born between 1975 and 1994 but declined among non-Hispanic black women, among whom risk by age 24 declined from 57.3% among women born between 1980 and 1984 to 38.6% among women born between 1990 and 1994. The lifetime risk of chlamydia-associated PID among women born between 1980 and 1984 ranged from 0.33% to 1.14%. Among non-Hispanic white, non-Hispanic black, and Hispanic women, the lifetime risk of chlamydia-associated TFI was 0.04%, 0.20%, and 0.10%, respectively. Conclusions:Over 60% of non-Hispanic black women had at least 1 chlamydia diagnosis by age 34 in the birth cohorts most affected, a risk almost 5 times that in non-Hispanic whites. An estimated 1 in 500 non-Hispanic black women develops chlamydia-associated TFI. More effective control measures are needed.

SUBMITTER: Chambers LC

PROVIDER: S-EPMC6070060 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Racial/Ethnic Disparities in the Lifetime Risk of Chlamydia trachomatis Diagnosis and Adverse Reproductive Health Outcomes Among Women in King County, Washington.

Chambers Laura C LC Khosropour Christine M CM Katz David A DA Dombrowski Julia C JC Manhart Lisa E LE Golden Matthew R MR

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20180801 4

<h4>Background</h4>Chlamydia trachomatis is the most common reportable infection in the United States and can cause pelvic inflammatory disease (PID) and tubal factor infertility (TFI).<h4>Methods</h4>We created life tables to estimate the "lifetime" risk of chlamydia diagnosis among women aged 15-34 years in King County, Washington, between 1992 and 2014. We estimated the lifetime risk of chlamydia-associated PID and TFI incorporating published estimates of the risk of sequelae.<h4>Results</h4> ...[more]

PMID: 29420716

Similar Datasets

Project description:Determining the causes of biological impairment in urban stream settings presents unique challenges because there are many potential stressors associated with human development. A rigorous, scientifically based process is more likely to identify influential stressors that can be reduced to improve stream condition. We used the U.S. Environmental Protection Agency's (U.S. EPA) CADDIS (Causal Analysis/Decision Information System) stressor identification process to assess eight candidate causes in the urban Soos Creek Basin in Washington State. The eight candidate causes capable of negatively affecting the abundance and diversity of benthic macroinvertebrates are: flow alteration, increased fine sediments, reduced habitat complexity, elevated water temperature, low dissolved oxygen, elevated nutrients, increased ionic concentration, and toxic pollutants. We assembled multiple lines of evidence, as well as the consistency of that evidence and agreement with other assessments. We evaluated the influence of natural and cumulative anthropogenic stressors on macroinvertebrate communities by comparing various chemical, physical, and biological measures at sites in the Soos Creek Basin with regional reference sites. Of the stressors evaluated, flow alteration, increased fine sediments, and loss of habitat complexity were the most probable causes of biological impairment, with multiple biological metrics responding predictably across levels of impairment. Key findings from this study include: the use of specific community alterations as evidence in causal assessment, demonstration of links in a complete causal pathway, and the use of multiple models to show which pathway is likely stronger. In addition to the value to the specific case, the analyses increased our understanding of the responses of stream invertebrate communities in urban environments. Ultimately, demonstrating the utility of causal assessment in a practical situation provides greater confidence that mitigation efforts aimed at improving biological health of urban stream communities will have detectable desired effects while also providing a baseline from which the effectiveness of management practices can be evaluated.

Dataset Information

Racial/Ethnic Disparities in the Lifetime Risk of Chlamydia trachomatis Diagnosis and Adverse Reproductive Health Outcomes Among Women in King County, Washington.

Publications

Racial/Ethnic Disparities in the Lifetime Risk of Chlamydia trachomatis Diagnosis and Adverse Reproductive Health Outcomes Among Women in King County, Washington.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets