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Breath biopsy for early detection and precision medicine in cancer.


ABSTRACT: Breath biopsy enables the non-invasive collection and analysis of volatile organic compounds (VOCs) in exhaled breath, providing valuable information about disease processes occurring in the body. Metabolic changes occur in cancer cells at the earliest stages of disease. We discuss progress in the use of breath biopsy for discovery of breath-based biomarkers for early detection of cancer, and potential applications for breath biopsy in enabling precision medicine in cancer.

SUBMITTER: van der Schee M 

PROVIDER: S-EPMC6070367 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Breath biopsy for early detection and precision medicine in cancer.

van der Schee Marc M   Pinheiro Hazel H   Gaude Edoardo E  

Ecancermedicalscience 20180719


Breath biopsy enables the non-invasive collection and analysis of volatile organic compounds (VOCs) in exhaled breath, providing valuable information about disease processes occurring in the body. Metabolic changes occur in cancer cells at the earliest stages of disease. We discuss progress in the use of breath biopsy for discovery of breath-based biomarkers for early detection of cancer, and potential applications for breath biopsy in enabling precision medicine in cancer. ...[more]

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