Ontology highlight
ABSTRACT:
SUBMITTER: Tong L
PROVIDER: S-EPMC6070564 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Tong Lu L Liu Jian J Yan Wangjun W Cao Wenjiao W Shen Shihui S Li Kun K Li Lei L Niu Guoping G
Scientific reports 20180801 1
RAD52 motif containing 1 (RDM1) is involved in DNA damage repair pathway and RDM1<sup>-/-</sup> cells increase sensitivity to cisplatin, a common chemotherapy drug. Lung cancer is the leading cause of cancer death worldwide. However, the role of RDM1 in lung cancer is unknown. Here, we find that the mRNA and protein expression levels of RDM1 are significantly increased in human lung tumors, especially in lung adenocarcinoma. The lung adenocarcinoma patients with higher mRNA expression of RDM1 sh ...[more]