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Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07.

ABSTRACT: Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages.

SUBMITTER: Jang G

PROVIDER: S-EPMC6070590 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07.

Jang Guehwan G Kim Seong-Hee SH Lee Yoo Jin YJ Kim Seungjoon S Lee Du Sik DS Lee Kyoung-Ki KK Lee Changhee C

Journal of veterinary science 20180701 4

Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least th ...[more]

PMID: 29695146

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