Functional Analysis of Promoters of Genes in Lipid Metabolism and Their Transcriptional Response to STAT3 under Leptin Signals.
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ABSTRACT:
SUBMITTER: Wu K
PROVIDER: S-EPMC6071087 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
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Functional Analysis of Promoters of Genes in Lipid Metabolism and Their Transcriptional Response to STAT3 under Leptin Signals.
Wu Kun K Tan Xiao-Ying XY Xu Yi-Huan YH Chen Guang-Hui GH Zhuo Mei-Qin MQ
Genes 20180703 7
We characterized the promoters of target genes of the signal transducer and activator of transcription 3, STAT3 (carnitine palmitoyltransferase I, <i>CPT Iα1b</i>, acetyl-CoA carboxylase alpha, <i>ACCα</i>; fatty acid synthase, <i>FAS</i>; and peroxisome proliferator-activated receptor gamma, <i>PPARγ</i>) in a teleost <i>Pelteobagrus fulvidraco</i>. Binding sites of STAT3 were predicted on these promoters, indicating that STAT3 probably mediated their transcriptional activitie ...[more]
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