Ontology highlight
ABSTRACT:
SUBMITTER: Monisha J
PROVIDER: S-EPMC6071146 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Monisha Javadi J Roy Nand Kishor NK Padmavathi Ganesan G Banik Kishore K Bordoloi Devivasha D Bordoloi Devivasha D Khwairakpam Amrita Devi AD Arfuso Frank F Chinnathambi Arunachalam A Alahmadi Tahani Awad TA Alharbi Sulaiman Ali SA Sethi Gautam G Kumar Alan Prem AP Kunnumakkara Ajaikumar B AB
Cancers 20180710 7
Oral cancer is a major public health burden worldwide. The lack of biomarkers for early diagnosis has increased the difficulty in managing this disease. Recent studies have reported that neutrophil gelatinase-associated lipocalin (NGAL), a secreted glycoprotein, is upregulated in various tumors. In our study, we found that NGAL was significantly downregulated in primary malignant and metastatic tissues of oral cancer in comparison to normal tissues. The downregulation of NGAL was strongly correl ...[more]