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Stable, Well-Defined Nickel(0) Catalysts for Catalytic C-C and C-N Bond Formation.

ABSTRACT: The synthesis and catalytic activity of several classes of NHC-Ni(0) pre-catalysts stabilized by electron-withdrawing alkenes are described. Variations in the structure of fumarate and acrylate ligands modulate the reactivity and stability of the NHC-Ni(0) pre-catalysts and lead to practical and versatile catalysts for a variety of transformations. The catalytic activity and efficiency of representative members of this class of catalysts have been evaluated in reductive couplings of aldehydes and alkynes and in N-arylations of aryl chlorides.

SUBMITTER: Nett AJ

PROVIDER: S-EPMC6071431 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Stable, Well-Defined Nickel(0) Catalysts for Catalytic C-C and C-N Bond Formation.

Nett Alex J AJ Cañellas Santiago S Higuchi Yuki Y Robo Michael T MT Kochkodan Jeanne M JM Haynes M Taylor MT Kampf Jeff W JW Montgomery John J

ACS catalysis 20180611 7

The synthesis and catalytic activity of several classes of NHC-Ni(0) pre-catalysts stabilized by electron-withdrawing alkenes are described. Variations in the structure of fumarate and acrylate ligands modulate the reactivity and stability of the NHC-Ni(0) pre-catalysts and lead to practical and versatile catalysts for a variety of transformations. The catalytic activity and efficiency of representative members of this class of catalysts have been evaluated in reductive couplings of aldehydes an ...[more]

PMID: 30079273

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