Unknown

Dataset Information

0

Cancer nanomedicine: from PDGF targeted drug delivery.

ABSTRACT: An innovative approach for the distinctively efficient action of smart targeted drug delivery to a specific cell type is obtained through the modification of the surface of nanoparticles. Specifically, the work identifies a cell surface receptor targeting drug delivery nanosystem based on mesoporous silica loaded with the anticancer drug cisplatin (cis-DDP) and poly-acrylic acid (PAA). A specific target is the PDGF receptors expressed in cervical cancer cells, thus making the PAA functionalized nanocomposite a suitable and promising nano-medicine for the targeting of PDGF-overexpressing cancers in the near future.

SUBMITTER: Rejeeth C 

PROVIDER: S-EPMC6071817 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Cancer nanomedicine: from PDGF targeted drug delivery.

Rejeeth Chandrababu C   Vivek Raju R   NipunBabu Varukattu V   Sharma Alok A   Ding Xianting X   Qian Kun K  

MedChemComm 20170928 11

An innovative approach for the distinctively efficient action of smart targeted drug delivery to a specific cell type is obtained through the modification of the surface of nanoparticles. Specifically, the work identifies a cell surface receptor targeting drug delivery nanosystem based on mesoporous silica loaded with the anticancer drug cisplatin (<i>cis</i>-DDP) and poly-acrylic acid (PAA). A specific target is the PDGF receptors expressed in cervical cancer cells, thus making the PAA function  ...[more]

Similar Datasets

Unknown Cancer nanomedicine: a review of recent success in drug delivery.
| S-EPMC5725398 | biostudies-other
Unknown Drug Resistance in Metastatic Breast Cancer: Tumor Targeted Nanomedicine to the Rescue.
| S-EPMC8125767 | biostudies-literature
Unknown Intrathecal drug delivery in the era of nanomedicine.
| S-EPMC8182643 | biostudies-literature
Unknown Efficient drug delivery and induction of apoptosis in colorectal tumors using a death receptor 5-targeted nanomedicine.
| S-EPMC4429693 | biostudies-literature
Unknown Targeted nanomedicine for suppression of CD44 and simultaneous cell death induction in ovarian cancer: an optimal delivery of siRNA and anticancer drug.
| S-EPMC3846837 | biostudies-literature
Unknown A multifunctional poly(curcumin) nanomedicine for dual-modal targeted delivery, intracellular responsive release, dual-drug treatment and imaging of multidrug resistant cancer cells.
| S-EPMC4847526 | biostudies-literature
Unknown Exosome-mimetic nanoplatforms for targeted cancer drug delivery.
| S-EPMC6637649 | biostudies-literature
Unknown Imaging Nanomedicine-Based Drug Delivery: a Review of Clinical Studies.
| S-EPMC6139024 | biostudies-literature
Unknown VIP-targeted Cytotoxic Nanomedicine for Breast Cancer.
| S-EPMC3546828 | biostudies-literature
Unknown Hypoxia-targeted drug delivery.
| S-EPMC6361706 | biostudies-literature