Peptide-fluorophore/AuNP conjugate-based two-photon excited fluorescent nanosensor for caspase-3 activity imaging assay in living cells and tissue.
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ABSTRACT:
SUBMITTER: Ge Q
PROVIDER: S-EPMC6071821 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Publications
Peptide-fluorophore/AuNP conjugate-based two-photon excited fluorescent nanosensor for caspase-3 activity imaging assay in living cells and tissue.
Ge Qingshan Q Wang Ningning N Li Jishan J Yang Ronghua R
MedChemComm 20170512 7
In the present study, a novel fluorescence resonance energy transfer (FRET) strategy-based two-photon excited nanosensor <i>via</i> the assembly of two-photon dye-labeled peptides on the gold nanoparticle's surface has been developed and successfully applied in the caspase-3 imaging assay in living cells and ischemia-reperfusion surgery-treated rat liver tissue slices. ...[more]
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