Ontology highlight
ABSTRACT:
SUBMITTER: Nijampatnam B
PROVIDER: S-EPMC6072251 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
ACS omega 20180730 7
Removal of oral biofilms involves the use of broad-spectrum antimicrobials, which eradicate both pathogenic and protective oral commensal species. Ideal therapeutics for dental caries should be able to selectively inhibit pathogenic biofilms caused by <i>Streptococcus mutans</i>. <i>S. mutans</i> extracellular glucosyltransferases (Gtfs), particularly GtfB and GtfC, synthesize predominantly water-insoluble glucans, which contribute to the structural scaffold of biofilms. The lead stilbene identi ...[more]