Multimodal neuromarkers in schizophrenia via cognition-guided MRI fusion.
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ABSTRACT:
SUBMITTER: Sui J
PROVIDER: S-EPMC6072778 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Publications
Multimodal neuromarkers in schizophrenia via cognition-guided MRI fusion.
Sui Jing J Qi Shile S van Erp Theo G M TGM Bustillo Juan J Jiang Rongtao R Lin Dongdong D Turner Jessica A JA Damaraju Eswar E Mayer Andrew R AR Cui Yue Y Fu Zening Z Du Yuhui Y Chen Jiayu J Potkin Steven G SG Preda Adrian A Mathalon Daniel H DH Ford Judith M JM Voyvodic James J Mueller Bryon A BA Belger Aysenil A McEwen Sarah C SC O'Leary Daniel S DS McMahon Agnes A Jiang Tianzi T Calhoun Vince D VD
Nature communications 20180802 1
Cognitive impairment is a feature of many psychiatric diseases, including schizophrenia. Here we aim to identify multimodal biomarkers for quantifying and predicting cognitive performance in individuals with schizophrenia and healthy controls. A supervised learning strategy is used to guide three-way multimodal magnetic resonance imaging (MRI) fusion in two independent cohorts including both healthy individuals and individuals with schizophrenia using multiple cognitive domain scores. Results hi ...[more]
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