Ontology highlight
ABSTRACT:
SUBMITTER: Joo HK
PROVIDER: S-EPMC6076278 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Joo Hyun Kyu HK Park Young Woo YW Jang Young Yoon YY Lee Jae Young JY
Scientific reports 20180803 1
Glutamine synthetase (GS) is an enzyme that regulates nitrogen metabolism and synthesizes glutamine via glutamate, ATP, and ammonia. GS is a homo-oligomeric protein of eight, ten, or twelve subunits, and each subunit-subunit interface has its own active site. GS can be divided into GS I, GS II, and GS III. GS I and GS III form dodecamer in bacteria and archaea, whereas GS II form decamer in eukaryotes. GS I can be further subdivided into GS I-α and GS I-β according to its sequence and regulatory ...[more]