Ontology highlight
ABSTRACT:
SUBMITTER: Combes F
PROVIDER: S-EPMC6076377 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Combes Francis F Mc Cafferty Séan S Meyer Evelyne E Sanders Niek N NN
Neoplasia (New York, N.Y.) 20180718 8
Solid tumors frequently coexist with a degree of local chronic inflammation. Recruited myeloid cells can therefore be considered as interesting vehicles for tumor-targeted delivery of therapeutic agents. Using in vivo imaging, the short-term accumulation of systemically injected monocytes, macrophages and myeloid-derived suppressor cells (MDSCs) was compared in mice bearing fat pad mammary carcinomas. Monocytes and macrophages demonstrated almost identical in vivo and ex vivo distribution patter ...[more]