Ontology highlight
ABSTRACT:
SUBMITTER: Mao D
PROVIDER: S-EPMC6077725 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Mao Dun D Neumann Adam R AR Sun Jianjun J Bonin Vincent V Mohajerani Majid H MH McNaughton Bruce L BL
Proceedings of the National Academy of Sciences of the United States of America 20180716 31
Retrosplenial cortex (RSC) is involved in visuospatial integration and spatial learning, and RSC neurons exhibit discrete, place cell-like sequential activity that resembles the population code of space in hippocampus. To investigate the origins and population dynamics of this activity, we combined longitudinal cellular calcium imaging of dysgranular RSC neurons in mice with excitotoxic hippocampal lesions. We tracked the emergence and stability of RSC spatial activity over consecutive imaging s ...[more]