Dataset Information

The influence of residual force enhancement on spinal and supraspinal excitability.

ABSTRACT:

Background

Following active muscle lengthening, there is an increase in steady-state isometric force as compared with a purely isometric contraction at the same muscle length and level of activation. This fundamental property of skeletal muscle is known as residual force enhancement (RFE). While the basic mechanisms contributing to this increase in steady-state isometric force have been well documented, changes in central nervous system (CNS) excitability for submaximal contractions during RFE are unclear. The purpose of this study was to investigate spinal and supraspinal excitability in the RFE isometric steady-state following active lengthening of the ankle dorsiflexor muscles.

Methods

A total of 11 male participants (20-28 years) performed dorsiflexions at a constant level of electromyographic activity (40% of maximum). Half of the contractions were purely isometric (8 s at an ankle angle of 130°), and the other half were during the RFE isometric steady-state following active lengthening (2 s isometric at 90°, a 1 s lengthening phase at 40°/s, and 5 s at 130°). Motor evoked potentials (MEPs), cervicomedullary motor evoked potentials (CMEPs), and compound muscle action potentials (M-waves) were recorded from the tibialis anterior during the purely isometric contraction and RFE isometric steady-state.

Results

Compared to the purely isometric condition, following active lengthening, there was 10% RFE (p < 0.05), with a 17% decrease in normalized CMEP amplitude (CMEP/M_max) (p < 0.05) and no change in normalized MEP amplitude (MEP/CMEP) (p > 0.05).

Discussion

These results indicate that spinal excitability is reduced during submaximal voluntary contractions in the RFE state with no change in supraspinal excitability. These findings may have further implications to everyday life offering insight into how the CNS optimizes control of skeletal muscle following submaximal active muscle lengthening.

SUBMITTER: Sypkes CT

PROVIDER: S-EPMC6078065 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Publications

The influence of residual force enhancement on spinal and supraspinal excitability.

Sypkes Caleb T CT Kozlowski Benjamin J BJ Grant Jordan J Bent Leah R LR McNeil Chris J CJ Power Geoffrey A GA

PeerJ 20180803

<h4>Background</h4>Following active muscle lengthening, there is an increase in steady-state isometric force as compared with a purely isometric contraction at the same muscle length and level of activation. This fundamental property of skeletal muscle is known as residual force enhancement (RFE). While the basic mechanisms contributing to this increase in steady-state isometric force have been well documented, changes in central nervous system (CNS) excitability for submaximal contractions duri ...[more]

PMID: 30083481

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Project description:Compared to pure isometric contractions, isometric muscle force at a given length is larger when the eccentric contraction is conducted before the isometric contraction. This phenomenon is widely known as residual force enhancement, and has been confirmed consistently in isolated muscle experiments. The purpose of this study was to confirm whether residual force enhancement also occurs in human plantar flexors and to examine its joint angle dependence. Eleven men participated in this study. Isometric joint torque was measured in a Control trial (pure isometric contraction) and Residual force enhancement (RFE) trial (isometric contraction after eccentric contraction) at plantar flexion 0° (Short condition) and dorsiflexion 15° (Long condition). Fascicle length and pennation angle of the medial gastrocnemius were measured simultaneously to evaluate the influence of architectural parameters on isometric joint torque. Isometric joint torque observed in the Short condition was not significantly different between the Control and RFE trials (Control: 42.9 ± 8.0 Nm, RFE: 45.1 ± 8.4 Nm) (p = 0.200). In contrast, significant differences in isometric joint torque were observed in the Long condition between Control and RFE trials (Control: 40.5 ± 9.3 Nm, RFE: 47.1 ± 10.5 Nm) (p = 0.001). Fascicle length and pennation angle were not different between Control and RFE trials in the Short and Long conditions. Isometric joint torque was larger when eccentric contraction was conducted before isometric contraction while architectural differences were not observed, indicating that residual force enhancement occurs in human plantar flexors. However, the influence of residual force enhancement may be limited in dorsiflexed positions because the magnitude of residual force enhancement is considered to be prominent in the descending limb (long muscle length condition) and small in the ascending limb (short muscle length condition) where human plantar flexors operate in plantar flexed positions.

Project description:BackgroundThe steady-state increase in muscle force generating potential following a lengthening contraction is called residual force enhancement (RFE). In this study, we aimed to test for differences in torque, electromyographic activity (EMG), and the associated neuromuscular efficiency (NME) between isometric voluntary contractions of elbow flexors preceded and not preceded by a lengthening contraction. The dependence of such differences on (i) stretch amplitude, (ii) the region of the force-length (FxL) relationship where contraction occurs, and (iii) the individual's ability to produce (negative) work during the stretch was investigated.MethodsSixteen healthy adults participated in the study. Elbow flexor torque, angle, and biceps brachii EMG for purely isometric contractions (reference contractions) and for isometric contractions preceded by active stretches of 20° and 40° were measured at the ascending, plateau, and descending regions of subject-specific FxL curves. All contractions were performed in an isokinetic dynamometer. Two-factor (stretch × FxL region) repeated measures analysis of variance ANOVAs was used to analyze the effect of active stretch on EMG, torque, and NME across conditions. The relationships between mechanical work during stretch-calculated as the torque-angular displacement integral-and the changes in EMG, torque, and NME were analyzed using Pearson correlation.ResultsIn general, torque, EMG, and NME following active stretches differed from the values observed for the purely isometric reference contractions. While although the detailed effects of active stretch on torque and EMG differed between regions of the FxL relationship, NME increased by about 19% for all muscle lengths. Up to 30% of the interindividual variability in torque generating potential change in response to active stretching was accounted for by differences in (negative) work capacity between subjects.ConclusionOur results suggest that (i) RFE contributes to "flatten" the elbow flexor torque-angle relationship, favoring torque production at lengths where the purely isometric torques are reduced substantially, and (ii) RFE contributes to a reduction in energy cost of torque production during isometric contractions for the entire operating range.

Project description:ObjectiveWe reviewed and appraised the existing evidence of in vivo manifestations of residual force enhancement in human skeletal muscles and assessed, through a meta-analysis, the effect of an immediate history of eccentric contraction on the subsequent torque capacity of voluntary and electrically evoked muscle contractions.MethodsOur search was conducted from database inception to May 2020. Descriptive information was extracted from, and quality was assessed for, 45 studies. Meta-analyses and metaregressions were used to analyze residual torque enhancement and its dependence on the angular amplitude of the preceding eccentric contraction.ResultsProcedures varied across studies with regards to muscle group tested, angular stretch amplitude, randomization of contractions, time window analyzed, and verbal command. Torque capacity in isometric (constant muscle tendon unit length and joint angle) contractions preceded by an eccentric contraction was typically greater compared to purely isometric contractions, and this effect was greater for electrically evoked muscle contractions than voluntary contractions. Residual torque enhancement differed across muscle groups for the voluntary contractions, with a significant enhancement in torque observed for the adductor pollicis, ankle dorsiflexors, ankle plantar flexors, and knee extensors, but not for the elbow and knee flexors. Meta-regressions revealed that the angular amplitude of the eccentric contraction (normalized to the respective joint's full range of motion) was not associated with the residual torque enhancement observed.ConclusionThere is evidence of residual torque enhancement for most, but not all, muscle groups, and residual torque enhancement is greater for electrically evoked than for voluntary contractions. Contrary to our hypothesis, and contrary to generally accepted findings on isolated muscle preparations, residual torque enhancement in voluntary and electrically evoked contractions does not seem to depend on the angular amplitude of the preceding eccentric contraction.

Dataset Information

The influence of residual force enhancement on spinal and supraspinal excitability.

Background

Methods

Results

Discussion

Publications

The influence of residual force enhancement on spinal and supraspinal excitability.

Similar Datasets

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