Ontology highlight
ABSTRACT:
SUBMITTER: Won SY
PROVIDER: S-EPMC6078854 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Molecules and cells 20180711 7
Leukocyte common antigen-related protein tyrosine phosphatases (LAR-RPTPs) are cellular receptors of heparan sulfate (HS) and chondroitin sulfate (CS) proteoglycans that regulate neurite outgrowth and neuronal regeneration. LAR-RPTPs have also received particular attention as the major presynaptic hubs for synapse organization through selective binding to numerous postsynaptic adhesion partners. Recent structural studies on LAR-RPTP-mediated <i>trans</i>-synaptic adhesion complexes have provided ...[more]