Ontology highlight
ABSTRACT:
SUBMITTER: Colvin TA
PROVIDER: S-EPMC6079565 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Colvin Teresa A TA Vachhani Pankit P Sait Sheila S Neppalli Vishala V Wang Eunice S ES
Leukemia research reports 20180725
A 78-year-old-male with chronic myeloid leukemia (CML) treated for seven years with dasatinib developed an acute promyelocytic leukemia complicated by disseminated intravascular coagulopathy. A promyelocytic blast crisis was diagnosed by demonstrating co-expression of chimeric <i>BCL/ABL</i> and <i>PML/RARα</i> translocations by karyotyping, fluorescence in situ hybridization, and quantitative real-time polymerase chain reaction. Promyelocytic blast crisis of CML is a rare event with historicall ...[more]