Ontology highlight
ABSTRACT:
SUBMITTER: Song Y
PROVIDER: S-EPMC6080406 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Song Yuri Y Na Hee Sam HS Park Eunjoo E Park Mi Hee MH Lee Hyun Ah HA Chung Jin J
International journal of oral science 20180806 3
Streptococcus mutans (S. mutans), a major aetiologic agent of dental caries, is involved in systemic diseases, such as bacterial endocarditis, if it enters the bloodstream through temporary bacteraemia. Interleukin (IL)-1β, a proinflammatory cytokine, is related to the host defences against pathogens, and its synthesis, maturation, and secretion are tightly regulated by the activation of the inflammasome, an inflammatory signalling complex. This study examined the signalling mechanism of IL-1β s ...[more]