Ontology highlight
ABSTRACT:
SUBMITTER: Moye AR
PROVIDER: S-EPMC6080659 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Moye Abigail R AR Singh Ratnesh R Kimler Victoria A VA Dilan Tanya L TL Munezero Daniella D Saravanan Thamaraiselvi T Goldberg Andrew F X AFX Ramamurthy Visvanathan V
Molecular biology of the cell 20180502 13
The outer segment (OS) of photoreceptor cells is an elaboration of a primary cilium with organized stacks of membranous disks that contain the proteins needed for phototransduction and vision. Though ciliary formation and function has been well characterized, little is known about the role of cilia in the development of photoreceptor OS. Nevertheless, progress has been made by studying mutations in ciliary proteins, which often result in malformed OSs and lead to blinding diseases. To investigat ...[more]