Ontology highlight
ABSTRACT:
SUBMITTER: Jemaa M
PROVIDER: S-EPMC6081478 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Jemaà Mohamed M Abassi Yasmin Y Kifagi Chamseddine C Fezai Myriam M Daams Renée R Lang Florian F Massoumi Ramin R
Scientific reports 20180807 1
Colorectal cancer is one of the most commonly diagnosed cancers and the third most common cause of cancer-related death. Metastasis is the leading reason for the resultant mortality of these patients. Accordingly, development and characterization of novel anti-cancer drugs limiting colorectal tumor cell dissemination and metastasis are needed. In this study, we found that the small molecule Reversine reduces the migration potential of human colon carcinoma cells in vitro. A coupled kinase assay ...[more]