Ontology highlight
ABSTRACT:
SUBMITTER: Liu JF
PROVIDER: S-EPMC6082132 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Liu Jessica F JF Yadavali Sagar S Tsourkas Andrew A Issadore David D
Lab on a chip 20171101 22
Diafiltration is a membrane filtration technique that rapidly removes permeable molecules from a solution by controlling the tangential and orthogonal flows over a membrane and by replenishing the permeate with an equivalent amount of replacement buffer. However, its application to the purification of many key biomaterials and nanomaterials has been limited by the large dead volume (>10 mL) that is required to automate the process. To address this challenge, we have developed a diafiltration-on- ...[more]