Ontology highlight
ABSTRACT:
SUBMITTER: Gamboa R
PROVIDER: S-EPMC6082227 | biostudies-literature | 2018 Apr./Jun
REPOSITORIES: biostudies-literature
Gamboa Ricardo R Huesca-Gómez Claudia C López-Pérez Vanessa V Posadas-Sánchez Rosalinda R Cardoso-Saldaña Guillermo G Medina-Urrutia Aida A Juárez-Rojas Juan Gabriel JG Soto María Elena ME Posadas-Romero Carlos C Vargas-Alarcón Gilberto G
Genetics and molecular biology 20180401 2
We examined the role of UCP gene polymorphisms as susceptibility markers for premature coronary artery disease (pCAD). The UCP2 Ala55Val (C/T rs660339), UCP2 -866G/A (rs659366), and UCP3 -55C/T (rs1800849) polymorphisms were genotyped in 948 patients with pCAD, and 763 controls. The distribution of the UCP2 A55V (C/T rs660339) and UCP3 -55 (rs1800849) was similar in patients and controls. However, under a recessive model, the UCP2 -866 (rs659366) A allele was associated with increased risk of de ...[more]