Ontology highlight
ABSTRACT:
SUBMITTER: Ahn J
PROVIDER: S-EPMC6082386 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Ahn Jeonghyun J Son Sehee S Oliveira Sergio C SC Barber Glen N GN
Cell reports 20171201 13
Intestinal immune homeostasis is preserved by commensal bacteria interacting with the host to generate a balanced array of cytokines that are essential for wound repair and for combatting infection. Inflammatory bowel disease (IBD), which can lead to colitis-associated cancer (CAC), is thought to involve chronic microbial irritation following a breach of the mucosal intestinal epithelium. However, the innate immune pathways responsible for regulating these inflammatory processes remain to be ful ...[more]