Ontology highlight
ABSTRACT:
SUBMITTER: Sawada Y
PROVIDER: S-EPMC6082864 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Sawada Yu Y Honda Tetsuya T Nakamizo Satoshi S Otsuka Atsushi A Ogawa Narihito N Kobayashi Yuichi Y Nakamura Motonobu M Kabashima Kenji K
Scientific reports 20180808 1
The potential of omega-3 poly-unsaturated fatty acids (PUFAs) as a therapeutic target for psoriasis, a chronic inflammatory skin disease of IL-23/IL-17 axis, is a long-disputed question, since various epidemiological studies have suggested the association between high-intake of omega-3 PUFAs and the reduced frequency and severity of psoriasis. However, their actual significance and the molecular mechanisms remain largely unknown. To address these issues, we focused on resolvin E1 (RvE1), an omeg ...[more]