Dataset Information

Robotic Kidney Transplantation from a Brain-Dead Deceased Donor in a Patient with Autosomal Dominant Polycystic Kidney Disease: First Case Report.

ABSTRACT: Background: Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of end-stage renal disease (ESRD) and may pose significant technical challenges for kidney transplantation. Recently, robot-assisted kidney transplantation (RAKT) has been shown to achieve excellent patient and graft outcomes while reducing surgical morbidity. However, the vast majority of RAKT performed so far were from living donors and no studies reported the outcomes of RAKT in patients with ADPKD. Case Presentation: Herein, we describe the first successful case of RAKT from a brain-dead deceased donor in a 37-year-old patient with ESRD due to ADPKD. Conclusion: Our case highlights that RAKT can be safely performed by experienced robotic surgeons even in selected complex recipients such as patients with ADPKD and using grafts from deceased donors.

SUBMITTER: Vignolini G

PROVIDER: S-EPMC6083208 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Robotic Kidney Transplantation from a Brain-Dead Deceased Donor in a Patient with Autosomal Dominant Polycystic Kidney Disease: First Case Report.

Vignolini Graziano G Sessa Francesco F Greco Isabella I Pili Alessandro A Giancane Saverio S Sebastianelli Arcangelo A Siena Giampaolo G Gacci Mauro M Li Marzi Vincenzo V Campi Riccardo R Serni Sergio S

Journal of endourology case reports 20180801 1

<b><i>Background:</i></b> Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of end-stage renal disease (ESRD) and may pose significant technical challenges for kidney transplantation. Recently, robot-assisted kidney transplantation (RAKT) has been shown to achieve excellent patient and graft outcomes while reducing surgical morbidity. However, the vast majority of RAKT performed so far were from living donors and no studies reported the outcomes of RAKT in patients with ADPK ...[more]

PMID: 30094337

Similar Datasets

Project description:BACKGROUND & AIMS:Polycystic liver disease (PLD), the most common extrarenal manifestation of autosomal-dominant polycystic kidney disease (ADPKD), has become more prevalent as a result of increased life expectancy, improved renal survival, reduced cardiovascular mortality, and renal replacement therapy. No studies have fully characterized PLD in large cohorts. We investigated whether liver and cyst volumes are associated with volume of the hepatic parenchyma, results from liver laboratory tests, and patient-reported outcomes. METHODS:We performed a cross-sectional analysis of baseline liver volumes, measured by magnetic resonance imaging, and their association with demographics, results from liver laboratory and other tests, and quality of life. The data were collected from a randomized, placebo-controlled trial underway at 7 tertiary-care medical centers to determine whether the combination of an angiotensin I-converting enzyme inhibitor and angiotensin II-receptor blocker was superior to the inhibitor alone, and whether low blood pressure (<110/75 mm Hg) was superior to standard blood pressure (120-130/70-80 mm Hg), in delaying renal cystic progression in 558 patients with ADPKD, stages 1 and 2 chronic kidney disease, and hypertension (age, 15-49 y). RESULTS:We found hepatomegaly to be common among patients with ADPKD. Cysts and parenchyma contributed to hepatomegaly. Cysts were more common and liver and cyst volumes were greater in women, increasing with age. Patients with advanced disease had a relative loss of liver parenchyma. We observed small abnormalities in results from liver laboratory tests, and that splenomegaly and hypersplenism were associated with PLD severity. Higher liver volumes were associated with a lower quality of life. CONCLUSIONS:Hepatomegaly is common even in early stage ADPKD and is not accounted for by cysts alone. Parenchymal volumes were larger, compared with liver volumes of patients without ADPKD or with those predicted by standardized equations, even among patients without cysts. The severity of PLD was associated with altered biochemical and hematologic features, as well as quality of life. ClinicalTrials.gov identifier: NCT00283686.

Dataset Information

Robotic Kidney Transplantation from a Brain-Dead Deceased Donor in a Patient with Autosomal Dominant Polycystic Kidney Disease: First Case Report.

Publications

Robotic Kidney Transplantation from a Brain-Dead Deceased Donor in a Patient with Autosomal Dominant Polycystic Kidney Disease: First Case Report.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets