Ontology highlight
ABSTRACT:
SUBMITTER: Choudhry P
PROVIDER: S-EPMC6083854 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Choudhry Priya P Galligan Derek D Wiita Arun P AP
Trends in cancer 20180627 8
For over a decade, the mainstay of multiple myeloma therapy has been small molecules that directly attack malignant plasma cell biology. However, potent immunotherapies have recently emerged, transforming the myeloma therapeutic landscape. Here we first review new promising strategies to target plasma cells through protein homeostasis and epigenetic modulators. We then discuss emerging immunotherapy strategies that are leading to dramatic results in patients. Finally, we focus on recent preclini ...[more]