ONETOOL for the analysis of family-based big data.

ABSTRACT: Motivation:Despite the need for separate tools to analyze family-based data, there are only a handful of tools optimized for family-based big data compared to the number of tools available for analyzing population-based data. Results:ONETOOL implements the properties of well-known existing family data analysis tools and recently developed methods in a computationally efficient manner, and so is suitable for analyzing the vast amount of variant data available from sequencing family members, providing a rich choice of analysis methods for big data on families. Availability and implementation:ONETOOL is freely available from http://healthstat.snu.ac.kr/software/onetool/. Supplementary information:Supplementary data are available at Bioinformatics online.

SUBMITTER: Song YE 

PROVIDER: S-EPMC6084591 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature