Ontology highlight
ABSTRACT:
SUBMITTER: Shiromani PJ
PROVIDER: S-EPMC6084767 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Shiromani Priyattam J PJ Peever John H JH
Sleep 20170401 4
The complexity of the brain is yielding to technology. In the area of sleep neurobiology, conventional neuroscience tools such as lesions, cell recordings, c-Fos, and axon-tracing methodologies have been instrumental in identifying the complex and intermingled populations of sleep- and arousal-promoting neurons that orchestrate and generate wakefulness, NREM, and REM sleep. In the last decade, new technologies such as optogenetics, chemogenetics, and the CRISPR-Cas system have begun to transform ...[more]