Ontology highlight
ABSTRACT:
SUBMITTER: Hosseini HS
PROVIDER: S-EPMC6085168 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Progress in biophysics and molecular biology 20180209
In the vertebrate embryo, the eyes develop from optic vesicles that grow laterally outward from the brain tube and contact the overlying surface ectoderm. Within the region of contact, each optic vesicle and the surface ectoderm thicken to form placodes, which then invaginate to create the optic cup and lens pit, respectively. Eventually, the optic cup becomes the retina, while the lens pit closes to form the lens vesicle. Here, we review current hypotheses for the physical mechanisms that creat ...[more]