Ontology highlight
ABSTRACT:
SUBMITTER: Demuth C
PROVIDER: S-EPMC6085225 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Demuth Christina C Spindler Karen-Lise Garm KG Johansen Julia S JS Pallisgaard Niels N Nielsen Dorte D Hogdall Estrid E Vittrup Benny B Sorensen Boe Sandahl BS
Translational oncology 20180804 5
Measuring total cell-free DNA (cfDNA) or cancer-specific mutations herein has presented as new tools in aiding the treatment of cancer patients. Studies show that total cfDNA bears prognostic value in metastatic colorectal cancer (mCRC) and that measuring cancer-specific mutations could supplement biopsies. However, limited information is available on the performance of different methods. Blood samples from 28 patients with mCRC and known KRAS mutation status were included. cfDNA was extracted a ...[more]