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Case Report: Ocular Microsporidiosis: Case in a Patient Returning from India and Review of the Literature.


ABSTRACT: Microsporidia are protists close to the kingdom of fungi that may cause eye infections. Most cases are reported in Asia and affect both immunocompromised and immunocompetent patients. Here, we report a rare case of microsporidial keratoconjunctivitis in an immunocompetent French patient 3 weeks after returning from India. In our patient, Weber trichrome staining of conjunctival scrapings revealed rounded elements approximately 1-3 ?m in size. Conventional polymerase chain reaction analysis by ribosomal RNA subunit sequencing showed 100% identity with Vittaforma corneae. Treatment by corneal debridement combined with fluoroquinolone eye drops allowed complete resolution of the lesions. Although rare, ocular microsporidiosis should be investigated in a patient who is native to Asia or has returned from an endemic area and presents with keratoconjunctivitis of undetermined etiology.

SUBMITTER: Leroy J 

PROVIDER: S-EPMC6085796 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Case Report: Ocular Microsporidiosis: Case in a Patient Returning from India and Review of the Literature.

Leroy Jordan J   Cornu Marjorie M   Deleplancque Anne-Sophie AS   Bart Aldert A   Loridant Séverine S   Fréalle Emilie E   Dutoit Emmanuel E   Gaillot Olivier O   van Gool Tom T   Puisieux François F   Labalette Pierre P   Sendid Boualem B  

The American journal of tropical medicine and hygiene 20180419 1


Microsporidia are protists close to the kingdom of fungi that may cause eye infections. Most cases are reported in Asia and affect both immunocompromised and immunocompetent patients. Here, we report a rare case of microsporidial keratoconjunctivitis in an immunocompetent French patient 3 weeks after returning from India. In our patient, Weber trichrome staining of conjunctival scrapings revealed rounded elements approximately 1-3 μm in size. Conventional polymerase chain reaction analysis by ri  ...[more]

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